U.S. Cannabis Stocks Are Ready for a Breakout

U.S. cannabis stocks such as Green Thumb are solid long-term bets for Canadian investors.

| More on:

Unlike Canadian cannabis companies, marijuana producers south of the border enjoy consistent profits and strong balance sheets. Several cannabis companies in the U.S. are multi-state operators, and a few of these regions are multi-billion markets.

Further, there is a possibility for cannabis to be legalized at the federal level, rapidly widening the total addressable markets for U.S. marijuana players. Several of these stocks are listed on the CNSX, making them accessible to Canadian investors.

Here are three such U.S. cannabis stocks that are ready for a breakout.

A person holds a small glass jar of marijuana.

Source: Getty Images

Curaleaf stock

Valued at a market cap of $3.5 billion, Curaleaf Holdings (CNSX:CURA) earned US$1.5 billion in sales in 2022. In Q1, its revenue surged 14% year over year to US$336 million, while international sales grew 53% to US$12.5 million. The medical and recreational marijuana dispenser reported an adjusted EBITDA (earnings before interest, tax, depreciation, and amortization) of US$71 million in Q1 and expects cash flows to range around US$55 million in 2023.

Curaleaf owns and operates 152 stores in 19 states, with 60 stores located in Florida, which is a limited-license market.

The cannabis giant also has a presence in Europe, a market that is forecast to touch US$14 billion by 2028, rising 53% annually. In order to lower its cost structure, Curaleaf shut down operations in a few facilities in California, Oregon, and Colorado.

But it also opened 26 new stores year to date, allowing Curaleaf to increase sales to US$2 billion in 2024. Analysts remain bullish on Curaleaf stock and expect it to gain 90% in the next 12 months.

Trulieve Cannabis stock

A vertically integrated marijuana producer, Trulieve Cannabis (CNSX:TRUL) is a major player in the medical marijuana market. It operates 125 medical cannabis dispensaries in Florida and enjoys a 50% market share in the sunshine state. Moreover, Trulieve also has dispensaries in nine other states, which include Nevada, California, and Arizona, with a total of 186 stores in the country.

It acquired Harvest Health & Recreation in October 2021, making Trulieve the largest U.S. cannabis company in terms of retail footprint.

Due to a challenging macro environment and rising competition, Trulieve’s sales in Q1 fell 9% to US$289 million. Comparatively, its adjusted EBITDA declined to US$78 million in the March quarter, compared to US$105 million in the year-ago period.

Valued at a market cap of US$1 billion, analysts expect Trulieve stock to more than triple in the next 12 months.

Green Thumb Industries stock

The final cannabis stock on my list is Green Thumb (CNSX:GTII), which reported sales of US$249 million in Q1, an increase of 2% year over year. While Green Thumb and its peers are currently wrestling with oversupply and pricing pressures, the company increased its sales from US$216 million in 2019 to US$1 billion in 2022.

Green Thumb operates in several limited-license markets allowing it to build a loyal customer base and generate stable earnings. For instance, it has now reported 10 consecutive quarters of positive GAAP (generally accepted accounting principles) net income.

Green Thumb operates 70 stores in 15 states, compared to 39 stores in eight states in 2019. While the company has used debt to fuel its growth, it ended the quarter with US$278 million in debt and US$185 million in cash. Its debt-to-equity multiple is quite low at 0.15 times.

Fool contributor Aditya Raghunath has no position in any of the stocks mentioned. The Motley Fool recommends Green Thumb Industries. The Motley Fool has a disclosure policy.

More on Cannabis Stocks

Yellow caution tape attached to traffic cone
Cannabis Stocks

2 Risky Stocks That Could Send Your $100,000 Investment to $0

Cannabis stocks look risky because price wars, dilution, and regulation can turn one weak quarter into a long drawdown.

Read more »

Pot stocks are a riskier investment
Cannabis Stocks

My Biggest Investing Regret in 2025 Was Buying This Stock

Canopy Growth is a cautionary reminder to buy businesses, not headlines, especially in hype-driven sectors like cannabis.

Read more »

Yellow caution tape attached to traffic cone
Cannabis Stocks

2 Popular Stocks That Could Wipe Out a $100,000 Nest Egg

Aurora Cannabis (TSX:ACB) is one stock that could wipe out your nest egg.

Read more »

Farmer smiles near cannabis crop
Cannabis Stocks

Here’s Why I Wouldn’t Touch Canopy Growth Stock With a 10-Foot Pole

Down almost 99% from all-time highs, Canopy Growth is a beaten-down cannabis stock that remains a high-risk investment in 2026.

Read more »

Cannabis business and marijuana industry concept as the shadow of a dollar sign on a group of leaves
Cannabis Stocks

2 Stocks That Could Turn $100,000 Into $0 Faster Than You Think

Canopy Growth and Plug Power are two unprofitable stocks that remain high-risk investments for shareholders in 2026.

Read more »

Pot stocks are a riskier investment
Cannabis Stocks

Will Canopy Growth Keep the Losing Streak Going in 2026?

Canopy Growth Corp (TSX:WEED) was one of the market's biggest losers in 2025.

Read more »

Farmer smiles near cannabis crop
Cannabis Stocks

TFSA Investors: An Undervalued Cannabis Stock You Can Buy for $500 Right Now

Down almost 70% from all-time highs, Curaleaf is a TSX cannabis stock that trades at an attractive valuation in December…

Read more »

Farmer smiles near cannabis crop
Cannabis Stocks

Can Canopy Growth Stock Finally Recover in 2026, as Donald Trump Might Ease Cannabis Restrictions?

Down over 99% from all-time highs, Canopy Growth stock might recover in 2026 if the Trump administration reclassifies cannabis products.

Read more »